Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth in two birth cohort studies.

doi:10.1186/1471-2350-10-67

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Article

Type 2 diabetes gene TCF7L2 polymorphism is not associated with fetal and postnatal growth in two birth cohort studies.

BMC medical genetics - 17 Jul 2009

Mook-Kanamori Dennis O, de Kort Sandra W K, van Duijn Cornelia M, Uitterlinden Andre G, Hofman Albert, Moll Henriëtte A, Steegers Eric A P, Hokken-Koelega Anita C S, Jaddoe Vincent W V

Abstract excerpt

BACKGROUND: An inverse association between birth weight and the risk of developing type 2 diabetes (T2D) in adulthood has been reported. This association may be explained by common genetic variants related to insulin secretion and resistance, since insulin is the most important growth factor in fetal life. The objective of this study was to examine whether T2D gene polymorphism TCF7L2 rs7903146 is associated with...

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PMID: 19615048
DOI: 10.1186/1471-2350-10-67
PMCID: PMC2722586

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