Article
Characterization of the patterns of drug-resistance mutations in newly diagnosed HIV-1 infected patients naïve to the antiretroviral drugs.
BMC infectious diseases - 16 Jul 2009
Alteri Claudia, Svicher Valentina, Gori Caterina, D'Arrigo Roberta, Ciccozzi Massimo, Ceccherini-Silberstein Francesca, Selleri Marina, Bardacci Stefano Aviani, Giuliani Massimo, Elia Paola, Scognamiglio Paola, Balzano Roberta, Orchi Nicoletta, Girardi Enrico, Perno Carlo Federico
Abstract excerpt
BACKGROUND: The transmission of HIV-1 drug-resistant strains in drug naive patients may seriously compromise the efficacy of a first-line antiretroviral treatment. To better define this problem, a study in a cohort of newly diagnosed HIV-1 infected individuals has been conducted. This study is aimed to assess the prevalence and the patterns of the mutations recently associated with transmitted drug resistance in...
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