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Article

A genetic polymorphism in transforming growth factor beta receptor-2 is associated with serum osteopontin.

International journal of immunogenetics - 1 Aug 2009

Biros E, Clancy P, Norman P E, Golledge J

Abstract excerpt

Osteopontin (OPN) is a secreted glycoprotein demonstrated to play an important role in inflammation. Transforming growth factor beta and a related signalling pathway have been implicated in control of OPN secretion. We examined the relationship between transforming growth factor beta receptor-1 and -2 (TGFBR1 and 2) single nucleotide polymorphisms (SNP) and serum OPN in 296 men from the Health in Men Study. Serum...

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Source

Identifiers

PMID: 19601999
DOI: 10.1111/j.1744-313X.2009.00855.x

Genes

TGFBR2
TGFBR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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