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Article

Prevalence of the C677T single-nucleotide polymorphism in the methylenetetrahydrofolate reductase gene among Pakistani ethnic groups.

Genetic testing and molecular biomarkers - 1 Aug 2009

Mansoor Atika, Mazhar Kehkashan, Ali Lubna, Muazzam Ambreen G, Siddiqi Saima, Usman Sooda

Abstract excerpt

Methylenetetrahydrofolate reductase is an important enzyme in metabolism of homocysteine, and a mutation in the gene predisposes individuals to several disorders related to homocysteine levels. Polymorphism at C677T shows marked heterogeneity based upon ethnicity and geographical location. Pakistani population consists of various ethnic groups confined to different regions of the country where congenital and...

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PMID: 19594369
DOI: 10.1089/gtmb.2009.0012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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