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Article

Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of Hemochromatosis

8 Jul 2009

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Share to Hemoglobinopathies and Related Disorders
Share to Iron Metabolism and Disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19591830
DOI: 10.1053/j.gastro.2009.06.057

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bone Morphogenetic Protein Signaling Is Impaired in an Hfe Knockout Mouse Model of HemochromatosisPMID 19591830Read ↗

Altered hepatic BMP signaling pathway in human HFE hemochromatosisSemantic proximity Read ↗

Bone status in a mouse model of genetic hemochromatosis.Semantic proximity Read ↗

HFE gene knockout produces mouse model of hereditary hemochromatosisSemantic proximity Read ↗

Defective Bone Morphogenic Protein Signaling Underlies Hepcidin Deficiency in HFE Hereditary HemochromatosisSemantic proximity Read ↗

Tmprss6 is a genetic modifier of the Hfe-hemochromatosis phenotype in mice.Semantic proximity Read ↗

The hemochromatosis protein HFE signals predominantly via the BMP type I receptor ALK3 in vivoSemantic proximity Read ↗

Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.Semantic proximity Read ↗

Common variants in the BMP2, BMP4, and HJV genes of the hepcidin regulation pathway modulate HFE hemochromatosis penetrance.Semantic proximity Read ↗

Bone phenotyping of murine hemochromatosis models with deficiencies of Hjv, Alk2, or Alk3: The influence of sex and the bone compartment.Semantic proximity Read ↗

Haptoglobin modifies the hemochromatosis phenotype in mice.Semantic proximity Read ↗

Genes that modify the hemochromatosis phenotype in mice.Semantic proximity Read ↗

BMP/Smad signaling is not enhanced in Hfe-deficient mice despite increased Bmp6 expressionSemantic proximity Read ↗

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