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Article

Insights into the beaded filament of the eye lens.

Experimental cell research - 10 Jun 2007

Perng Ming-Der, Zhang Qingjiong, Quinlan Roy A

Abstract excerpt

Filensin (BFSP1) and CP49 (BFSP2) represent two members of the IF protein superfamily that are thus far exclusively expressed in the eye lens. Mutations in both proteins cause lens cataract and careful consideration of the detail of these cataract phenotypes alerts us to several interesting features concerning the function of filensin (BFSP1) and CP49 (BFSP2) in the lens. With the first filensin (BFSP1) mutation...

Topics

Animals
Cataract
Epithelial Cells
Eye Proteins
Genetic Predisposition to Disease
Humans
Intermediate Filament Proteins
Intermediate Filaments
Lens, Crystalline
Mutation
Protein Structure, Tertiary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

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Identifiers

PMID: 17490642
DOI: 10.1016/j.yexcr.2007.04.005
PMCID: PMC5073188

Genes

BFSP1
BFSP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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