Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insights into the beaded filament of the eye lens.

Experimental cell research - 10 Jun 2007

Perng Ming-Der, Zhang Qingjiong, Quinlan Roy A

Abstract excerpt

Filensin (BFSP1) and CP49 (BFSP2) represent two members of the IF protein superfamily that are thus far exclusively expressed in the eye lens. Mutations in both proteins cause lens cataract and careful consideration of the detail of these cataract phenotypes alerts us to several interesting features concerning the function of filensin (BFSP1) and CP49 (BFSP2) in the lens. With the first filensin (BFSP1) mutation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cataract
Share to Epithelial Cells
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Intermediate Filament Proteins

Share to Intermediate Filaments

Share to Lens, Crystalline

Share to Protein Structure, Tertiary

Source

Open in PubMed Open full text

Identifiers

PMID: 17490642
DOI: 10.1016/j.yexcr.2007.04.005
PMCID: PMC5073188

Genes

BFSP1
BFSP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insights into the beaded filament of the eye lens.PMID 17490642Read ↗

Functions of the intermediate filament cytoskeleton in the eye lens.Semantic proximity Read ↗

A novel beaded filament structural protein 1 (BFSP1) gene mutation associated with autosomal dominant congenital cataract in a Chinese family.Semantic proximity Read ↗

Novel mega-deletion in BFSP1 causing autosomal recessive juvenile cataract in a Pakistani consanguineous family.Semantic proximity Read ↗

Autosomal recessive juvenile onset cataract associated with mutation in BFSP1.Semantic proximity Read ↗

A juvenile-onset, progressive cataract locus on chromosome 3q21-q22 is associated with a missense mutation in the beaded filament structural protein-2.Semantic proximity Read ↗

A new mutation in BFSP2 (G1091A) causes autosomal dominant congenital lamellar cataracts.Semantic proximity Read ↗

Clinical description and genome wide linkage study of Y-sutural cataract and myopia in a Chinese family.Semantic proximity Read ↗

The eye lens cytoskeleton.Semantic proximity Read ↗

A novel p.G112E mutation in BFSP2 associated with autosomal dominant pulverulent cataract with sutural opacities.Semantic proximity Read ↗

Resisting the effects of aging: a function for the fiber cell beaded filament.Semantic proximity Read ↗

D348N Mutation of BFSP1 Gene in Congenital Cataract: it Does Matter.Semantic proximity Read ↗

Inbred FVB/N mice are mutant at the cp49/Bfsp2 locus and lack beaded filament proteins in the lens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.