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Article

Identification of amino acids in the dengue virus type 2 envelope glycoprotein critical to virus infectivity.

The Journal of general virology - 1 Oct 2009

Kroschewski Helga, Sagripanti Jose-Luis, Davidson Andrew D

Abstract excerpt

The dengue virus envelope glycoprotein mediates virus attachment and entry and is the major viral antigen. The identification of 'critical' amino acids in the envelope glycoprotein that cannot be altered without loss of infectivity could have a major impact on the development of dengue virus vaccines and diagnostics. In this context, we determined whether six amino acids, previously predicted by computational...

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Identifiers

PMID: 19587132
DOI: 10.1099/vir.0.011486-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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