Article
Association of FTO variants with BMI and fat mass in the self-contained population of Sorbs in Germany.
European journal of human genetics : EJHG - 1 Jan 2010
Tönjes Anke, Zeggini Eleftheria, Kovacs Peter, Böttcher Yvonne, Schleinitz Dorit, Dietrich Kerstin, Morris Andrew P, Enigk Beate, Rayner Nigel W, Koriath Moritz, Eszlinger Markus, Kemppinen Anu, Prokopenko Inga, Hoffmann Katrin, Teupser Daniel, Thiery Joachim, Krohn Knut, McCarthy Mark I, Stumvoll Michael
Abstract excerpt
The association between common variants in the FTO gene with weight, adiposity and body mass index (BMI) has now been widely replicated. Although the causal variant has yet to be identified, it most likely maps within a 47 kb region of intron 1 of FTO. We performed a genome-wide association study in the Sorbian population and evaluated the relationships between FTO variants and BMI and fat mass in this isolate of...
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