Article
Association study between BDNF gene polymorphisms and autism by three-dimensional gel-based microarray.
International journal of molecular sciences - 2 Jun 2009
Cheng Lu, Ge Qinyu, Xiao Pengfeng, Sun Beili, Ke Xiaoyan, Bai Yunfei, Lu Zuhong
Abstract excerpt
Single nucleotide polymorphisms (SNPs) are important markers which can be used in association studies searching for susceptible genes of complex diseases. High-throughput methods are needed for SNP genotyping in a large number of samples. In this study, we applied polyacrylamide gel-based microarray combined with dual-color hybridization for association study of four BDNF polymorphisms with autism. All the SNPs...
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