Article
Depletion of peripheral blood B cells with Rituximab and phenotype characterization of the recovering population in a patient with follicular lymphoma.
Leukemia research - 1 Mar 2010
Abulayha Abdulmunem M, Tabal Salah A, Shawesh Eman I, Elbasir Mohamed A, Elbanani Abdulrhman S, Lamami Yosra M, Bredan Amin
Abstract excerpt
The monoclonal antibody Rituximab is useful for treatment of patients with B-cell non-Hodgkin's lymphoma. We phenotypically analyzed reconstitution of peripheral B cells in a male patient with follicular lymphoma following their depletion with Rituximab. CD19+ and CD20+ B cell counts in peripheral blood decreased rapidly following Rituximab treatment. Six months after the end of treatment, a few CD19+ B cells...
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