Article
Pol bootscanning analysis of HIV type 1 can exhibit unexpected recombinations.
AIDS research and human retroviruses - 1 Jul 2009
Jeannot Anne-Cécile, Reigadas Sandrine, Schrive Marie-Helene, Pinson Patricia, Fleury Herve J
Abstract excerpt
In France the recommendation is to sequence the RT gene of HIV-1 isolates prior to initiation of antiretroviral therapy. The data are routinely used for molecular characterization of the viruses yielding the subtype or CRF of the isolates investigated together with the absence or presence of drug resistance mutations. In this study, we performed bootscanning analysis on the whole pol gene, in which in vitro and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.