Article
Evidence for transmission disequilibrium at the DAOA gene locus in a schizophrenia family sample.
Neuroscience letters - 22 Sept 2009
Ma Jie, Sun Jian, Zhang Huan, Zhang Rui, Kang Wan-Hu, Gao Cheng-Ge, Liu Hai-Sheng, Ma Xue-Hong, Min Zi-Xin, Zhao Wen-Xiang, Ning Qi-Lan, Wang Shu-Hong, Zhang Yin-Cang, Guo Ting-Wei, Lu She-Min
Abstract excerpt
Recently, the DAOA gene locus on chromosome 13q32-q34 has been implicated in the etiology of schizophrenia. We genotyped three single-nucleotide polymorphisms (SNPs: rs778294, rs779293 and rs3918342) in this region in 126 Chinese family trios. In this study, we have identified statistically significant transmission disequilibrium in two markers rs778293 (P=0.01) and rs3918342 (P=0.02), and a highly significant...
