Hepatic lipase promoter C-480T polymorphism is associated with serum lipids levels, but not subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.

doi:10.1111/j.1399-0004.2009.01180.x

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Article

Hepatic lipase promoter C-480T polymorphism is associated with serum lipids levels, but not subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study.

Clinical genetics - 1 Jul 2009

Fan Y-M, Raitakari O T, Kähönen M, Hutri-Kähönen N, Juonala M, Marniemi J, Viikari J, Lehtimäki T

Abstract excerpt

The common C-480T polymorphism (rs1800588) of the hepatic lipase gene (LIPC) has been associated with high-density lipoprotein (HDL) cholesterol, atherosclerosis, and coronary artery disease. In this study, we examined whether the polymorphism is associated with serum lipid and lipoprotein concentrations, as well as with subclinical atherosclerosis in Young Finns. The participants comprised 2041 men and women...

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PMID: 19558527
DOI: 10.1111/j.1399-0004.2009.01180.x

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LIPC

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