Article
Influence of MBL-2 mutations in the infection risk of patients with follicular lymphoma treated with rituximab, fludarabine, and cyclophosphamide.
Leukemia & lymphoma - 1 Aug 2009
Martínez-López Joaquin, Rivero Ana, Rapado Inmaculada, Montalbán Carlos, Paz-Carreira Jose, Canales Miguel, Martínez Rafael, Sánchez-Godoy Pedro, Fernández de Sevilla Alberto, Peñalver Francisco J, Gonzalez Marcos, Prieto Elena, Salar Antonio, Burgaleta Carmen, Queizán Jose A, Peñarrubia Maria J, Monteagudo Maria D, Cabrera Carmen, De la Serna Javier, Tomás José F
Abstract excerpt
The employment of current treatments based on chemotherapy and immunotherapy leads to inmunosuppression. The presence of mutations or polymorphisms in genes related to immune system might involve an additional disadvantage. The aim of the present study was to analyze mannose-binding lectin (MBL-2 gene) mutations and their association with severe infections and event-free survival in patients diagnosed with...
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