Article
Investigating genomic imprinting and susceptibility to insulin-dependent diabetes mellitus: an epidemiologic approach.
Genetic epidemiology - 1 Jan 1991
McCarthy B J, Dorman J S, Aston C E
Abstract excerpt
Children of fathers with insulin-dependent diabetes mellitus (IDDM) are at greater risk of developing the disease than are children of IDDM mothers, reasons for which are currently unknown. To explore the possibility that genomic imprinting contributes to this phenomenon, 1,774 families with at least one IDDM child diagnosed before the age of 17 years and between 1950 and 1981 from the Children's Hospital at...
Topics
- Adolescent
- Adult
- Child
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Female
- Genetic Predisposition to Disease
- Humans
- Life Tables
- Male
- Middle Aged
- Pennsylvania