Article
Parent-of-origin specific linkage and association of the IGF2 gene region with birth weight and adult metabolic risk factors.
International journal of obesity (2005) - 1 Sept 2009
Souren N Y, Paulussen A D C, Steyls A, Loos R J F, Brandao R D, Gielen M, Smeets H J M, Beunen G, Fagard R, Derom C, Vlietinck R, Geraedts J P, Zeegers M P
Abstract excerpt
OBJECTIVE: The maternally imprinted insulin-like growth factor 2 (IGF2) gene is an important fetal growth factor and is also suggested to have postnatal metabolic effects. In this study, we examined whether common polymorphisms in IGF2 (6815_6819delAGGGC, 1156T>C and 820G>A (ApaI)) and a microsatellite marker in the close vicinity of IGF2 were linked to or associated with birth weight and adult metabolic risk...
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