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Article

Influence of recombination on development of mutational resistance to linezolid in Enterococcus faecalis JH2-2.

Antimicrobial agents and chemotherapy - 1 Sept 2009

Boumghar-Bourtchaï Leyla, Dhalluin Anne, Malbruny Brigitte, Galopin Sébastien, Leclercq Roland

Abstract excerpt

We compared the propensities of Enterococcus faecalis JH2-2 and of the recombination-deficient JH2-2 recA strain to develop mutational resistance to linezolid. In both organisms, a mutation in a single rrl copy conferred resistance to linezolid. Delay in acquisition of the mutation by other rrl c...

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Identifiers

PMID: 19546366
DOI: 10.1128/AAC.01633-08
PMCID: PMC2737844

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19546366-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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