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Article

Modulation of RecFORQ- and RecA-Mediated Homologous Recombination in Escherichia coli by Isoforms of Translation Initiation Factor IF2.

Journal of bacteriology - 19 Apr 2022

Mallikarjun Jillella, SaiSree L, Himabindu P, Anupama K, Reddy Manjula, Gowrishankar J

Abstract excerpt

Homologous recombination (HR) is critically important for chromosomal replication, as well as DNA damage repair in all life forms. In Escherichia coli, the process of HR comprises (i) two parallel presynaptic pathways that are mediated, respectively, by proteins RecB/C/D and RecF/O/R/Q; (ii) a synaptic step mediated by RecA that leads to generation of Holliday junctions (HJs); and (iii) postsynaptic steps...

Topics

Bacterial Proteins
DNA Helicases
Escherichia coli
Escherichia coli Proteins
Homologous Recombination
Humans
Mutation
Peptide Initiation Factors
Protein Isoforms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35343793
DOI: 10.1128/jb.00569-21
PMCID: PMC9017302

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