Article
The contributions of resistin and adiponectin gene single nucleotide polymorphisms to the genetic risk for polycystic ovary syndrome in a Japanese population.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Aug 2009
Baba Tsuyoshi, Endo Toshiaki, Sata FuMihiro, Nagasawa Kunihiko, Honnma Hiroyuki, Kitajima Yoshimitsu, Hayashi Takuhiro, Manase Kengo, Kanaya Mika, Moriwaka Osamu, Kamiya Hirofumi, Yamada Hideto, Minakami Hisanori, Kishi Reiko, Saito Tsuyoshi
Abstract excerpt
Polycystic ovary syndrome (PCOS) is a heterogeneous group of disorders that occur fairly commonly in women of reproductive age and are characterized by a variety of clinical manifestations, including insulin resistance that is independent of obesity. Recent studies suggest that altered adipocytokine gene expression is closely associated with insulin resistance and that single nucleotide polymorphisms (SNPs)...
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