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Article

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells

16 Aug 2009

Abstract excerpt

beclin 1, the mammalian homologue of the yeast Atg6, is a key autophagy-promoting gene that plays a critical role in the regulation of cell death and survival of various types of cells. However, recent studies have observed that the expression of beclin 1 is altered in certain diseases including cancers. The causes underlying the aberrant expression of beclin 1 remain largely unknown. We report here that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 19535919
DOI: 10.4161/auto.9064

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