Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miR-30b, Down-Regulated in Gastric Cancer, Promotes Apoptosis and Suppresses Tumor Growth by Targeting Plasminogen Activator Inhibitor-1

29 Aug 2014

Abstract excerpt

BACKGROUND: Gastric cancer is one of the most common malignant diseases worldwide. Emerging evidence has shown that microRNAs (miRNAs) are associated with tumor development and progression. Our previous studies have revealed that H. pylori infection was able to induce the altered expression of miR-30b in gastric epithelial cells. However, little is known about the potential role of miR-30b in gastric cancer....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular RNAs in diseases
Share to Cytokine Signaling Pathways and Interactions
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25170877
DOI: 10.1371/journal.pone.0106049

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miR-30b, Down-Regulated in Gastric Cancer, Promotes Apoptosis and Suppresses Tumor Growth by Targeting Plasminogen Activator Inhibitor-1PMID 25170877Read ↗

CASC15 mediated upregulation of SERPINE1 by sponging miR-30c- 5p correlates with poor prognosis and immune infiltration of gastric cancerSemantic proximity Read ↗

Polymorphism in pre-miR-30c contributes to gastric cancer risk in a Chinese population.Semantic proximity Read ↗

miR-30b inhibits cancer cell growth, migration, and invasion by targeting homeobox A1 in esophageal cancer.Semantic proximity Read ↗

Clinicopathological role of miR-30a-5p in hepatocellular carcinoma tissues and prediction of its function with bioinformatics analysisSemantic proximity Read ↗

Knockdown of angiopoietin-like 4 inhibits the development of human gastric cancerSemantic proximity Read ↗

MicroRNA-28 promotes cell proliferation and invasion in gastric cancer via the PTEN/PI3K/AKT signalling pathwaySemantic proximity Read ↗

MicroRNA-30b-5p functions as a metastasis suppressor in colorectal cancer by targeting Rap1bSemantic proximity Read ↗

microRNA-372 maintains oncogene characteristics by targeting TNFAIP1 and affects NFκB signaling in human gastric carcinoma cells.Semantic proximity Read ↗

MicroRNA-18a modulates STAT3 activity through negative regulation of PIAS3 during gastric adenocarcinogenesisSemantic proximity Read ↗

Association of Beclin-1 and microRNA-30a expression with the severity and treatment response of colorectal cancerSemantic proximity Read ↗

Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cellsSemantic proximity Read ↗

Mutation R273H confers p53 a stimulating effect on the IGF-1R-AKT pathway via miR-30a suppression in breast cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.