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Article

Protein aggregation as a paradigm of aging.

Biochimica et biophysica acta - 1 Oct 2009

Lindner Ariel B, Demarez Alice

Abstract excerpt

The process of physiological decline leading to death of the individual is driven by the deteriorating capacity to withstand extrinsic and intrinsic hazards, resulting in damage accumulation with age. The dynamic changes with time of the network governing the outcome of misfolded proteins, exemplifying as intrinsic hazards, is considered here as a paradigm of aging. The main features of the network, namely, the...

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PMID: 19527771
DOI: 10.1016/j.bbagen.2009.06.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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