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Article

Transcriptomes and pathways associated with infectivity, survival and immunogenicity in Brugia malayi L3

1 Jan 2009

Abstract excerpt

BACKGROUND: Filarial nematode parasites cause serious diseases such as elephantiasis and river blindness in humans, and heartworm infections in dogs. Third stage filarial larvae (L3) are a critical stage in the life cycle of filarial parasites, because this is the stage that is transmitted by arthropod vectors to initiate infections in mammals. Improved understanding of molecular mechanisms associated with this...

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PMID: 19527522
DOI: 10.1186/1471-2164-10-267

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