Article
A comparison of two methods for screening CEBPA mutations in patients with acute myeloid leukemia.
The Journal of molecular diagnostics : JMD - 1 Jul 2009
Ahn Jeung-Yeal, Seo Katie, Weinberg Olga, Boyd Scott D, Arber Daniel A
Abstract excerpt
The goal of the study was to compare the performance of a fluorescence-based multiplex PCR fragment analysis to a direct sequencing method for detecting CEBPA mutations in patients with acute myeloid leukemia. Thirty-three samples were selected from a larger study of 107 cases of acute myeloid leukemia by screening for CEBPA mutations by sequence analysis. Of ten identified mutations, six (insertions and...
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