Article
Modulation of eDNA release and degradation affects Staphylococcus aureus biofilm maturation.
PloS one - 9 Jun 2009
Mann Ethan E, Rice Kelly C, Boles Blaise R, Endres Jennifer L, Ranjit Dev, Chandramohan Lakshmi, Tsang Laura H, Smeltzer Mark S, Horswill Alexander R, Bayles Kenneth W
Abstract excerpt
Recent studies have demonstrated a role for Staphylococcus aureus cidA-mediated cell lysis and genomic DNA release in biofilm adherence. The current study extends these findings by examining both temporal and additional genetic factors involved in the control of genomic DNA release and degradation during biofilm maturation. Cell lysis and DNA release were found to be critical for biofilm attachment during the...
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