Article
The role of geography in human adaptation.
PLoS genetics - 1 Jun 2009
Coop Graham, Pickrell Joseph K, Novembre John, Kudaravalli Sridhar, Li Jun, Absher Devin, Myers Richard M, Cavalli-Sforza Luigi Luca, Feldman Marcus W, Pritchard Jonathan K
Abstract excerpt
Various observations argue for a role of adaptation in recent human evolution, including results from genome-wide studies and analyses of selection signals at candidate genes. Here, we use genome-wide SNP data from the HapMap and CEPH-Human Genome Diversity Panel samples to study the geographic distributions of putatively selected alleles at a range of geographic scales. We find that the average allele frequency...
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