Article
Large allele frequency differences between human continental groups are more likely to have occurred by drift during range expansions than by selection.
Annals of human genetics - 1 Jan 2009
Hofer T, Ray N, Wegmann D, Excoffier L
Abstract excerpt
Several studies have found strikingly different allele frequencies between continents. This has been mainly interpreted as being due to local adaptation. However, demographic factors can generate similar patterns. Namely, allelic surfing during a population range expansion may increase the frequency of alleles in newly colonised areas. In this study, we examined 772 STRs, 210 diallelic indels, and 2834 SNPs typed...
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