Article
The impact of divergence time on the nature of population structure: an example from Iceland.
PLoS genetics - 1 Jun 2009
Price Alkes L, Helgason Agnar, Palsson Snaebjorn, Stefansson Hreinn, St Clair David, Andreassen Ole A, Reich David, Kong Augustine, Stefansson Kari
Abstract excerpt
The Icelandic population has been sampled in many disease association studies, providing a strong motivation to understand the structure of this population and its ramifications for disease gene mapping. Previous work using 40 microsatellites showed that the Icelandic population is relatively homogeneous, but exhibits subtle population structure that can bias disease association statistics. Here, we show that...
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