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A reassessment of genetic diversity in Icelanders: strong evidence from multiple loci for relative homogeneity caused by genetic drift.

Annals of human genetics - 1 Jul 2003

Helgason A, Nicholson G, Stefánsson K, Donnelly P

Abstract excerpt

There has been some controversy in the literature concerning whether Icelanders are genetically homogenous or heterogeneous relative to other European populations. We reassess this question in the light of large data sets spanning 83 autosomal SNP loci, 14 serogenetic loci, 6622 Y-chromosomes and 3214 sequences from mtDNA hypervariable segments 1 and 2 (HVS1 and HVS2). Our results strongly support the hypothesis...

Topics

Chromosomes, Human, Y
Computer Simulation
DNA, Mitochondrial
Genetic Drift
Genetic Variation
Genetics, Population
Haplotypes
Humans
Iceland
Male
Models, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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Identifiers

PMID: 12914564
DOI: 10.1046/j.1469-1809.2003.00046.x

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