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Article

Identification of a bioactive compound isolated from Brazilian propolis type 6.

Bioorganic & medicinal chemistry - 15 Jul 2009

Castro Myrella Lessio, do Nascimento Andréa Mendes, Ikegaki Masaharu, Costa-Neto Cláudio M, Alencar Severino M, Rosalen Pedro L

Abstract excerpt

A prenylated benzophenone, hyperibone A, was isolated from the hexane fraction of Brazilian propolis type 6. Its structure was determined by spectral analysis including 2D NMR. This compound exhibited cytotoxic activity against HeLa tumor cells (IC(50)=0.1756microM), strong antimicrobial activity (MIC range-0.73-6.6microg/mL; MBC range-2.92-106microg/mL) against Streptococcus mutans, Streptococcus sobrinus,...

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Identifiers

PMID: 19497755
DOI: 10.1016/j.bmc.2009.04.066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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