Article
Antineoplastic Agents. 551. Isolation and Structures of Bauhiniastatins 1−4 from <i>Bauhinia </i><i>p</i><i>urpurea</i>
15 Nov 2005
Abstract excerpt
Bioassay-guided (P388 lymphocytic leukemia cell line) separation of extracts prepared from the leaves, stems, and pods of Bauhinia purpurea, and, in parallel, its roots, led to the isolation of four new dibenz[b,f]oxepins (2a, 3-5) named bauhiniastatins 1-4, as well as the known and related pacharin (1) as cancer cell growth inhibitors. The occurrence of oxepin derivatives in nature is quite rare. Bauhiniastatins...
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