Article
[Cyto-genotoxicity induced by cigarette smoke condensates in human peripheral blood lymphocytes in vitro].
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases - 1 Mar 2009
Lou Jian-lin, Zhou Guo-jun, Chu Guo-hai, Huang Fang-fang, Jiang Jian, Zheng Shu, Lu Ye-zhen, Li Xiao-xue, Chen Zhi-jian, He Ji-liang
Abstract excerpt
OBJECTIVE: To investigate the cyto-genotoxicity of cigarette smoke condensates (CSCs) in human peripheral blood lymphocytes with different assays in vitro. METHODS: Human lymphocytes were exposed to particle matter of cigarette smoke combined with or without S9 mixtures at doses of 25, 50, 75, 100 and 125 microg/ml for 3 h. The cytotoxicity induced by CSCs was detected by CCK-8 assay. The DNA damage, DNA repair...
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