Article
RET/PTC rearrangements arising from a small population of papillary thyroid carcinoma cells, possible candidate for passenger mutation.
Virchows Archiv : an international journal of pathology - 1 Jul 2009
Nakazawa Tadao, Murata Shin-ichi, Kondo Tetsuo, Niu Dongfeng, Mochizuki Kunio, Kawasaki Tomonori, Yamane Tetsu, Nakamura Nobuki, Katoh Ryohei
Abstract excerpt
RET rearrangements (RET/PTC) is a major genetic alteration in papillary thyroid carcinomas. However, the prevalence of RET/PTC differs considerably among investigators, and its impact on cancer progression has been controversial. In the current study, we applied interphase fluorescence in situ hybridization (FISH) to touch imprint cytology of 14 papillary thyroid carcinomas along with reverse-transcription...
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