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Article

RET rearrangements and BRAF mutation in undifferentiated thyroid carcinomas having papillary carcinoma components.

Histopathology - 1 Sept 2010

Mochizuki Kunio, Kondo Tetsuo, Nakazawa Tadao, Iwashina Masanori, Kawasaki Tomonori, Nakamura Nobuki, Yamane Tetsu, Murata Shin-ichi, Ito Koichi, Kameyama Kaori, Kobayashi Makio, Katoh Ryohei

Abstract excerpt

AIMS: To elucidate the genetic background of anaplastic transformation, RET rearrangements and BRAF mutation were studied in composite undifferentiated carcinomas (UCs) of the thyroid, which are UCs having papillary carcinoma (PC) components. METHODS AND RESULTS: Reverse transcription-polymerase chain reaction (RT-PCR) was performed for RET rearrangements and PCR for BRAF mutation in UC and PC components that...

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Source

Identifiers

PMID: 20840674
DOI: 10.1111/j.1365-2559.2010.03646.x

Genes

RET
BRAF

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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