Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GM-CSF restoration of a differentiated (growth factor-regulated) phenotype in an anaplastic tumor.

Urological research - 1 Jan 1991

Rubenstein M, Shaw M, Targonski P, McKiel C F, Dubin A, Guinan P

Abstract excerpt

GM-CSF (granulocyte-macrophage-derived colony-stimulating factor) is a differentiation agent that stimulates bone marrow activity in patients receiving chemotherapy. GM-CSF (1 microgram/ml daily for 10 days), administered intralesionally, was evaluated to determine whether it would restore a more differentiated phenotype to an anaplastic, rapidly growing, hormone-independent variant (R3327 MAT-LyLu) of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to ErbB Receptors
Share to Neoplasm Transplantation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Phenotype

Share to Prostatic Neoplasms

Share to Rats, Inbred Strains

Share to Recombinant Proteins

Source

Identifiers

PMID: 1949430
DOI: 10.1007/BF00299066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

GM-CSF restoration of a differentiated (growth factor-regulated) phenotype in an anaplastic tumor.PMID 1949430Read ↗

Expression and function of colony-stimulating factors and their receptors in human prostate carcinoma cell linesSemantic proximity Read ↗

Reduced FRG1 expression promotes prostate cancer progression and affects prostate cancer cell migration and invasionSemantic proximity Read ↗

Improvement in predicting tumorigenic phenotype of androgen-insensitive human LNCaP prostatic cancer cell subline in recombination with rat urogenital sinus mesenchyme.Semantic proximity Read ↗

Granulin <sup>+</sup> macrophages promote lineage plasticity in prostate cancer through paracrine signaling loopsSemantic proximity Read ↗

MZF1-mediated GAPDH overexpression drives glycolytic reprogramming and neuroendocrine progression in advanced prostate cancerSemantic proximity Read ↗

Osteomimetic properties of prostate cancer cells: a hypothesis supporting the predilection of prostate cancer metastasis and growth in the bone environment.Semantic proximity Read ↗

Human prostate cancer precursors and pathobiologySemantic proximity Read ↗

Tumors of the Testis: Morphologic Features and Molecular Alterations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.