Article
GM-CSF restoration of a differentiated (growth factor-regulated) phenotype in an anaplastic tumor.
Urological research - 1 Jan 1991
Rubenstein M, Shaw M, Targonski P, McKiel C F, Dubin A, Guinan P
Abstract excerpt
GM-CSF (granulocyte-macrophage-derived colony-stimulating factor) is a differentiation agent that stimulates bone marrow activity in patients receiving chemotherapy. GM-CSF (1 microgram/ml daily for 10 days), administered intralesionally, was evaluated to determine whether it would restore a more...
Topics
- Adenocarcinoma
- Animals
- ErbB Receptors
- Granulocyte-Macrophage Colony-Stimulating Factor
- Male
- Neoplasm Transplantation
- Phenotype
- Prostatic Neoplasms
- Rats
- Rats, Inbred Strains
- Recombinant Proteins
- Testosterone
