Article
Correlation between flow cytometric identification of CD33-positive cells and morphological evaluation of myeloblasts in bone marrow of patients with acute myeloblastic leukemia.
Hematology (Amsterdam, Netherlands) - 1 Jun 2009
Oka Satoko, Muroi Kazuo, Matsuyama Tomohiro, Sato Kazuya, Ueda Masuzu, Toshima Masaki, Suzuki Takahiro, Ozaki Katsutoshi, Mori Masaki, Takubo Takayuki, Nagai Tadashi, Hanafusa Toshiaki, Ozawa Keiya
Abstract excerpt
Determination of the percentage of myeloblasts in bone marrow is important for the evaluation of acute myeloblastic leukemia (AML) and related disorders. Using flow cytometry with a CD45-blast gate (FCM/CD45), 226 bone marrow aspiration samples serially collected from 71 patients with de novo AML were analyzed. Bone marrow smears were evaluated independently by pathologists who did not know the corresponding flow...
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