Article
Predictive value of flow cytometric analyses of blast cells in assessing the phenotype of the leukemia colony-forming cell (L-CFC) population in acute myeloid leukemia.
Bone marrow transplantation - 1 Sept 1992
Howell A L, Stukel T A, Bloomfield C D, Ball E D
Abstract excerpt
Acute myeloid leukemia (AML) blast cells (BC) express antigens that are commonly found on their normal counterparts. The leukemia colony-forming cell (L-CFC) subpopulation, identified by its ability to form leukemia colonies in vitro, is thought to be the stem cell population that produces BC. To ascertain the association between myeloid antigens on the BC and the L-CFC from the same patient, we compared the...
Topics
- Antigens, Differentiation
- Bone Marrow Purging
- Bone Marrow Transplantation
- Flow Cytometry
- Humans
- Leukemia, Myeloid, Acute
- Neoplastic Stem Cells
- Phenotype
- Tumor Stem Cell Assay