Article
Set-up and routine use of a database of 10,555 genotyped blood donors to facilitate the screening of compatible blood components for alloimmunized patients.
Vox sanguinis - 1 Jul 2009
Perreault J, Lavoie J, Painchaud P, Côté M, Constanzo-Yanez J, Côté R, Delage G, Gendron F, Dubuc S, Caron B, Lemieux R, St-Louis M
Abstract excerpt
BACKGROUND AND OBJECTIVES: Large-scale genotyping of blood donors for red blood cell and platelet antigens has been predicted to replace phenotyping assays in the screening of compatible blood components for alloimmunized patients. Although several genotyping platforms have been described, novel procedures and processes are needed to perform genotyping efficiently and to maximize its benefits for blood banks....
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