Article
Translation regulation of integrons gene cassette expression by the attC sites.
Molecular microbiology - 1 Jun 2009
Jacquier Hervé, Zaoui Caroline, Sanson-le Pors Marie-Jose, Mazel Didier, Berçot Béatrice
Abstract excerpt
Integron are genetic elements able to carry, capture and shuffle the genes embedded in gene cassettes. The attC recombination sites adopt a stable secondary structure when single-stranded that is necessary for their recombination. In this study, we evaluated the impact of the structure of the attC site on expression of the 3' gene in class 1 integrons. This was analysed by substituting the attC of the bla(IMP-8)...
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