Article
Validity of low copy number typing and applications to forensic science.
Croatian medical journal - 1 Jun 2009
Budowle Bruce, Eisenberg Arthur J, van Daal Angela
Abstract excerpt
Low copy number (LCN) typing, particularly for current short tandem repeat (STR) typing, refers to the analysis of any sample that contains less than 200 pg of template DNA. Generally, LCN typing simply can be defined as the analysis of any DNA sample where the results are below the stochastic threshold for reliable interpretation. There are a number of methodologies to increase sensitivity of detection to enable...
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