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Rimonabant inhibits human colon cancer cell growth and reduces the formation of precancerous lesions in the mouse colon

6 Apr 2009

Abstract excerpt

The selective CB1 receptor antagonist rimonabant (SR141716) was shown to perform a number of biological effects in several pathological conditions. Emerging findings demonstrate that rimonabant exerts antitumor action in thyroid tumors and breast cancer cells. In our study, human colorectal cancer cells (DLD-1, CaCo-2 and SW620) were treated with rimonabant and analyzed for markers of cell proliferation, cell...

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PMID: 19479993
DOI: 10.1002/ijc.24483

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