Article
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1).
Acta crystallographica. Section F, Structural biology and crystallization communications - 1 Jun 2009
Mayerhofer Hubert, Schramm Gabriele, Hatzopoulos Georgios N, Mueller-Dieckmann Christoph, Haas Helmut, Mueller-Dieckmann Jochen
Abstract excerpt
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) triggers the release of large amounts of interleukin-4 from human blood basophils, thus presumably playing an immunomodulatory role during schistosome infection. IPSE/alpha-1 was crystallized and a native X-ray data set was collected to 1.66 A resolution from a single crystal at 100 K using synchrotron radiation. The crystal...
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