Article
Mannose-binding lectin null alleles are associated with preserved epithelial cell integrity following intestinal ischemia reperfusion in man.
Molecular immunology - 1 Jul 2009
Matthijsen R A, Derikx J P M, Steffensen R, van Dam R M, Dejong C H C, Buurman W A
Abstract excerpt
Mannose-binding lectin (MBL) deficiency is associated with reduced intestinal ischemia-reperfusion (IR) damage in rodents. We set out to investigate an association between frequently observed MBL deficiency and IR associated intestinal cell damage in man. Using a newly developed IR model of the human small intestine 29 patients were consecutively included. Part of the jejunum was subjected to 30 min of ischemia...
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