Prediction of the site of signal peptidase cleavage in normal and variant human preproalbumin.

Article

Prediction of the site of signal peptidase cleavage in normal and variant human preproalbumin.

Protein sequences & data analysis - 1 Aug 1991

Peach R J, Boswell D R, Brennan S O

Abstract excerpt

We describe the use of a template for the recognition site of signal peptidase to give score predictions for cleavage at normal and aberrant sites in human and chicken preproalbumin. As expected, the highest score obtained for human preproalbumin was at the normal cleavage site between -7 Ser and...

Topics

Algorithms
Amino Acid Sequence
Animals
Chickens
Endopeptidases
Humans
Membrane Proteins
Molecular Sequence Data
Mutation
Prealbumin
Protein Precursors
Serine Endopeptidases
Software
Templates, Genetic

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