Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Telomere length in peripheral blood mononuclear cells is associated with folate status in men.

The Journal of nutrition - 1 Jul 2009

Paul Ligi, Cattaneo Marco, D'Angelo Armando, Sampietro Francesca, Fermo Isabella, Razzari Cristina, Fontana Gessica, Eugene Nindra, Jacques Paul F, Selhub Jacob

Abstract excerpt

Human chromosomes are capped by telomeres, which consist of tandem repeats of DNA and associated proteins. The length of the telomeres is reduced with increasing cell divisions except when the enzyme telomerase is active, as in stem cells and germ cells. Telomere dysfunction has been associated with development of age-related pathologies, including cancer, cardiovascular disease, Alzheimer's disease, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Globins
Share to Cellular Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Folic Acid

Share to Homocysteine

Share to Leukocytes, Mononuclear

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Telomere

Share to Vitamin B 12

Source

Identifiers

PMID: 19458030
DOI: 10.3945/jn.109.104984

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Telomere length in peripheral blood mononuclear cells is associated with folate status in men.PMID 19458030Read ↗

Telomere dynamics: the influence of folate and DNA methylationSemantic proximity Read ↗

Effects of MTHFR A1298C polymorphism on peripheral blood folate concentration in healthy populations: a meta-analysis of observational studies.Semantic proximity Read ↗

Association of Folate Metabolites and Mitochondrial Function in Peripheral Blood Cells in Alzheimer’s Disease: A Matched Case-Control StudySemantic proximity Read ↗

DNA Methylation of Human Telomerase Reverse Transcriptase Associated With Leukocyte Telomere Length Shortening in Hyperhomocysteinemia-Type Hypertension in Humans and in a Rat ModelSemantic proximity Read ↗

Telomere length is age-dependent and reduced in monocytes of Alzheimer patientsSemantic proximity Read ↗

Study of telomere length in men who carry a fragile X premutation or full mutation allele.Semantic proximity Read ↗

Reduced telomere length in older men with premutation alleles of the fragile X mental retardation 1 gene.Semantic proximity Read ↗

Folate deficiency is not associated with increased mitochondrial genomic instability: results from dietary intake and lymphocytic mtDNA 4977-bp deletion in healthy young women in Italy.Semantic proximity Read ↗

Homocysteine, methylenetetrahydrofolate reductase C677T polymorphism and cognitive impairment: the health in men study.Semantic proximity Read ↗

The relationship between MTHFR genotype, serum homocysteine and folate levels.Semantic proximity Read ↗

Functional variants in CYP1B1, KRAS and MTHFR genes are associated with shorter telomere length in postmenopausal women.Semantic proximity Read ↗

Reduced breast cancer risk with increasing serum folate in a case-control study of the C677T genotype of the methylenetetrahydrofolate reductase gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.