Article
Androgen, progesterone, and FSH receptor polymorphisms in ovarian cancer risk and outcome.
Endocrine-related cancer - 1 Sept 2009
Ludwig Agnieszka Honorata, Murawska Magdalena, Panek Grzegorz, Timorek Agnieszka, Kupryjanczyk Jolanta
Abstract excerpt
Genes encoding hormone receptors are among candidate genes modulating the risk of ovarian cancer. We aimed to assess a frequency of PGRG+331A, FSHRAla307Thr, and FSHRSer680Asn polymorphic variants, and the length of (CAG)n and (GGN)n repeat tracts in the androgen receptor gene (AR) with respect to ovarian cancer risk and outcome. We genotyped 215 ovarian cancer patients and 352 unaffected control subjects....
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