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Article

p21 Expression by human urothelial carcinoma cells modulates the phenotypic response to BCG.

Urologic oncology - 1 Jan 2000

See William A, Zhang Guangjian, Chen Fanghong, Cao Yanli

Abstract excerpt

PURPOSE: The direct phenotypic effects of BCG on human urothelial carcinoma (UC) cells include cell cycle arrest, apoptotic resistance, and caspase-independent cell death. These effects are associated with increased expression of the cyclin dependant kinase inhibitor (CDKI) p21. This study assessed the role of p21 expression in mediating the phenotypic effects observed in response to BCG. MATERIALS AND METHODS:...

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Identifiers

PMID: 19450997
DOI: 10.1016/j.urolonc.2008.12.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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