Article
[Immunological aspects of anticancer chemotherapy].
Bulletin de l'Academie nationale de medecine - 1 Oct 2008
Zitvogel Laurence, Tesniere Antoine, Apetoh Lionel, Ghiringhelli François, Kroemer Guido
Abstract excerpt
For over 40 years, four therapeutic modalities, namely surgery, radiotherapy, chemotherapy and hormone therapy have formed the core of anticancer treatments. Their mode of action is thought to involve a direct cytotoxic action on tumor cells. Recently, the discovery of tumor-associated immunosuppression and tumor immunosurveillance has led to cancer being reconsidered not only as an organ disease but also as a...
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