Article
[Free circulating DNA based colorectal cancer screening from peripheral blood: the possibility of the methylated septin 9 gene marker].
Orvosi hetilap - 24 May 2009
Tóth Kinga, Galamb Orsolya, Spisák Sándor, Wichmann Barnabás, Sipos Ferenc, Leiszter Katalin, Molnár Jeannette, Molnár Béla, Tulassay Zsolt
Abstract excerpt
DNA methylation acts in early tumorigenesis. Its detection is possible either from tissue, stool or peripheral blood. Septin 9 is a sensitive methylation marker, which has been studied in several cancers such as breast and ovarian tumors and in neurological or hematological diseases. Septin proteins have an important role from cytoskeleton organisation to development of embryonal pattern. Nowadays intensive...
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