Association of Methylenetetrahydrofolate Reductase rs1801133 Gene Polymorphism with Cancer Risk and Septin 9 Methylation in Patients with Colorectal Cancer.

doi:10.1007/s12029-024-01020-y

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Association of Methylenetetrahydrofolate Reductase rs1801133 Gene Polymorphism with Cancer Risk and Septin 9 Methylation in Patients with Colorectal Cancer.

Journal of gastrointestinal cancer - 1 Jun 2024

Huang Yafei, Su Ting, Duan Qiuting, Wei Xiangcong, Fan Xin, Wan Jinxiu, Liu Luping, Dian Ziqin, Zhang Guiqian, Sun Yi, Zhou Tao, Xu Ya

Abstract excerpt

PURPOSE: Colorectal cancer (CRC) is one of the most common malignancies, with a high incidence and mortality worldwide. Methylated Septin 9 (mSEPT9) has been used clinically as an auxiliary tool for CRC screening. The aim of the present study was to investigate the association of the methylenetetrahydrofolate reductase (MTHFR) rs1801133 polymorphism with the risk of CRC and the methylation status of Septin 9 in...

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PMID: 38252186
DOI: 10.1007/s12029-024-01020-y
PMCID: PMC11186932

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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